Transcriptome Analysis of Porcine PBMCs Reveals the Immune Cascade Response and Gene Ontology Terms Related to Cell Death and Fibrosis in the Progression of Liver Failure

Background.The key gene sets involved in the progression of acute liver failure (ALF), which has a high mortality rate, remain unclear.This study aims to gain a deeper understanding of the transcriptional response of peripheral blood mononuclear cells (PBMCs) following ALF.Methods.ALF was induced by D-galactosamine (D-gal) in a porcine model.PBMCs

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Inverse Kinematics Solution of Articulated Robots Using a Heuristic Approach for Optimizing Joint Displacement

In this work, a new constrained numerical optimization approach is proposed for solving offline the Inverse Kinematics Problem (IKP) of articulated robots, which consists on optimizing the joint displacement while the end effector is positioned and oriented in a desired pose.The novelty of this approach is in the formulation of the optimization pro

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